Background: T1R1 (TR1, GPR70, gm148, taste receptor type 1 member 1, TAS1R1) is a G protein-coupled receptor and is a component of the heterodimeric amino acid taste receptor T1R1+3. T1R1+3 responds to L-amino acids that are perceived as sweet. Multiple transcript variants encoding several different isoforms have been found for this gene. The T1R receptors are a family of taste-specific class C G protein-coupled receptors. PLCbeta2 and IP(3)R3 co-localize together with G(i2) as downstream components of two different types of taste receptors, T1R and T2R, in taste bud cells.
Description: Rabbit polyclonal to GPCR TAS1R1
Immunogen: KLH conjugated synthetic peptide derived from GPCR TAS1R1
Specificity: ·Reacts with Human, Mouse and Rat.
·Isotype: IgG
Application: ·Western blotting: 1/100-500. Predicted Mol wt: 93 kDa;
·Immunohistochemistry (Paraffin/frozen tissue section): 1/50-200;
·Immunocytochemistry: 1/100;
·Immunofluorescence: 1/50-200;
·ELISA: 1/500;
·Optimal working dilutions must be determined by the end user.
