Background: Epidermal growth factor (EGF) repeat-containing proteins constitute an expanding family of proteins that are involved in several cellular activities, such as blood coagulation, fibrinolysis, cell adhesion, and neural and vertebrate development. In addition, this family encodes proteins that govern cellular proliferative responses. EGFL6, a human EGF repeat superfamily member that maps to human chromosome X, encodes a predicted signal peptide suggesting that it is secreted. Other predicted features include four and one-half EGF-like repeat domains, two N-linked glycosylation sites, an integrin association motif, and a tyrosine phosphorylation site. EGFL6 is expressed in brain and lung tumors and fetal tissues, but is generally absent from normal adult tissues.
Description: Rabbit polyclonal to EGFL6
Immunogen: KLH conjugated synthetic peptide derived from EGFL6
Specificity: ·Reacts with Human, Mouse and Rat.
·Isotype: IgG
Application: ·Western blotting: 1/100-500. Predicted Mol wt: 61 kDa;
·Immunohistochemistry (Paraffin/frozen tissue section): 1/50-200;
·Immunocytochemistry/Immunofluorescence: 1/100;
·Immunoprecipitation: 1/50;
·ELISA: 1/500;
·Optimal working dilutions must be determined by the end user.
