Background: BAT9, also known as Protein G10 or ZBTB12 (zinc finger and BTB domain containing 12), is a 459 amino acid protein that may be involved in transcriptional regulation. BAT9 localizes to nucleus, contains one BTB (POZ) domain and four C2H2-type zinc fingers. The BAT9 gene maps to human chromosome 6p21.32. Making up nearly 6% of the human genome, chromosome 6 contains around 1,200 genes within 170 million base pairs of sequence. Porphyria cutanea tarda is associated with chromosome 6 through the HFE gene which, when mutated, predisposes an individual to developing this porphyria. Notably, the PARK2 gene, which is associated with Parkinson's disease, and the genes encoding the major histocompatiblity complex proteins, which are key molecular components of the immune system and determine predisposition to rheumatic diseases, are also located on chromosome 6.
Description: Rabbit polyclonal to ZBTB12
Immunogen: KLH conjugated synthetic peptide derived from ZBTB12
Specificity: ·Reacts with Human, Mouse, Pig, Dog and Rat.
·Isotype: IgG
Application: ·Western blotting: 1/100-500. Predicted Mol wt: 49 kDa;
·Immunohistochemistry (Paraffin/frozen tissue section): 1/50-200;
·Immunocytochemistry/Immunofluorescence: 1/100;
·Immunoprecipitation: 1/50;
·ELISA: 1/500;
·Optimal working dilutions must be determined by the end user.
