Background: TMTSP (transmembrane molecule with Thrombospondin module), also known as THSD1 (Thrombospondin type-1 domain-containing protein 1), is an 852 amino acid protein expressed in endothelial cells and hematopoietic cells. Three isoforms of TMTSP are produced by alternative splicing events. Isoforms 1 and 2 are single-pass type I membrane proteins while isoform 3 is a secreted protein. TMTSP contains three immunoglobulin-like domains and one Thrombospondin domain. Thrombospondin domains have been associated with cell migration and are found in a variety of different proteins, including extracellular matrix proteins, thromobospondins and complement pathway proteins.
Description: Rabbit polyclonal to THSD1
Immunogen: KLH conjugated synthetic peptide derived from THSD1
Specificity: ·Reacts with Human, Mouse and Rat.
·Isotype: IgG
Application: ·Western blotting: 1/100-500. Predicted Mol wt: 89 kDa;
·Immunohistochemistry (Paraffin/frozen tissue section): 1/50-200;
·Immunocytochemistry/Immunofluorescence: 1/100;
·Immunoprecipitation: 1/50;
·ELISA: 1/500;
·Optimal working dilutions must be determined by the end user.
