Background: IGSF9B (immunoglobulin superfamily member 9B), also known as protein turtle homolog B or KIAA1030, is a 1,349 amino acid single-pass type I membrane protein that belongs to the immunoglobulin superfamily and turtle family. Members of this family of proteins usually localize to the cell membrane, and may act as receptors in immune response pathways. Containing two fibronectin type-III domains and five Ig-like (immunoglobulin-like) domains, IGSF9B may be involved in cell signaling. IGSF9B is highly expressed in brain, with lower levels of expression found in heart, testis, ovary, liver, skeletal muscle, spinal cord and fetal brain. The gene encoding IGSF9B maps to human chromosome 11, which houses over 1,400 genes and comprises nearly 4% of the human genome. Jervell and Lange-Nielsen syndrome, Jacobsen syndrome, Niemann-Pick disease, hereditary angioedema and Smith-Lemli-Opitz syndrome are associated with defects in genes that maps to chromosome 11.
Description: Rabbit polyclonal to IGSF9B
Immunogen: KLH conjugated synthetic peptide derived from IGSF9B
Specificity: ·Reacts with Human, Mouse and Rat.
·Isotype: IgG
Application: ·Western blotting: 1/100-500. Predicted Mol wt: 147 kDa;
·Immunohistochemistry (Paraffin/frozen tissue section): 1/50-200;
·Immunocytochemistry/Immunofluorescence: 1/100;
·Immunoprecipitation: 1/50;
·ELISA: 1/500;
·Optimal working dilutions must be determined by the end user.
