Background: Placenta-specific proteins (PLACs) are X-linked proteins. The Plac1 gene maps to a region of the X chromosome known to be important for placental growth. Plac1 shows placenta-specific expression and is considered a marker for placental development. PLAC1 may play a role establishing the mother-fetus interface and is expressed exclusively by cells of trophoblastic lineage. PLAC1 expression is upregulated during trophoblast differentiation and its expression is regulated by peptide growth factors. It is detectable in maternal blood, but rapidly disappears after delivery.
Description: Rabbit polyclonal to phospho-PLAC1(Tyr147)
Immunogen: A synthesized phosphopeptide derived from PLAC1 around the phosphorylation site of Tyr147.
Specificity: ·Reacts with Human, Mouse and Rat.
·Isotype: IgG
Application: ·Western blotting: 1/100-500. Predicted Mol wt: 24 kDa;
·Immunohistochemistry (Paraffin/frozen tissue section): 1/50-200;
·Immunocytochemistry: 1/100;
·Immunoprecipitation: 1/50;
·ELISA: 1/500;
·Optimal working dilutions must be determined by the end user.
