Background: TPO (thyroid peroxidase) is single-pass type I membrane-bound glycoprotein, iodinates tyrosine residues in thyroglobulin to generate biologically active thyroid hormones T3 and T4.and Iodination and coupling of the hormonogenic tyrosines in thyroglobulin to yield the thyroid hormones T(3) and T(4). Binds 1 calcium ion per heterodimer. Belongs to the peroxidase family. XPO subfamily.
Description: Rabbit polyclonal to TPO
Immunogen: KLH conjugated synthetic peptide derived from TPO
Specificity: ·Reacts with Human, Mouse and Rat.
·Isotype: IgG
Application: ·Western blotting: 1/100-500. Predicted Mol wt: 103 kDa;
·Immunohistochemistry (Paraffin/frozen tissue section): 1/100-500;
·Immunocytochemistry: 1/200;
·ELISA: 1/500;
·Optimal working dilutions must be determined by the end user.
