Background: Ndufs4 is the first multisubunit enzyme complex of the mitochondrial respiratory chain, and plays a vital role in cellular ATP production, the primary source of energy for many crucial processes in living cells. It removes electrons from NADH and passes them to the electron acceptor ubiquinone by a series of different protein-coupled redox centers. In well-coupled mitochondria, the electron flux leads to ATP generation via the building of a proton gradient across the inner membrane. It is composed of at least 41 subunits, of which 7 are encoded by the mitochondrial genome and the remainder by nuclear genes.
Description: Rabbit polyclonal to NDUFS4
Immunogen: KLH conjugated synthetic peptide derived from NDUFS4
Specificity: ·Reacts with Human, Mouse and Rat.
·Isotype: IgG
Application: ·Western blotting: 1/100-500. Predicted Mol wt: 18 kDa;
·Immunohistochemistry (Frozen/paraffin tissue section): 1/100-500;
·Immunocytochemistry: 1/100-500;
·ELISA: 1/500;
·Optimal working dilutions must be determined by the end user.
