Background: ABCB5 is a plasma membrane transporter able to mediate efflux from cells of the rhodamine dye and of the therapeutic drug doxorubicin. ABCB5 is also responsible for the resistance to doxorubicin of a subset of malignant melanomas. ABCB5 has more recently been identified as a marker for human malignant-melanoma-initiating cells.
Description: Rabbit polyclonal to ABCB5
Immunogen: KLH conjugated synthetic peptide derived from ABCB5
Specificity: ·Reacts with Human, Mouse, Dog, Cow and Rat.
·Isotype: IgG
Application: ·Western blotting: 1/200-1000. Predicted Mol wt: 138 kDa;
·Immunohistochemistry (Frozen/paraffin tissue section): 1/100-500;
·Immunocytochemistry: 1/100-500;
·ELISA: 1/1000;
·Optimal working dilutions must be determined by the end user.
