Background: ATP7b is an important protein for copper transport and elimination of excess copper from the body. ATP7b transports metals in and out of cells using ATP. There are 3 known isoforms of the ATP7b gene; A is found in the liver, kidney, and brain, the shorter form B is found in brain tissue, and the third isoform, known as WND/140 KDA is found in mitochondria. Mutations in the ATP7b gene can cause Wilson's disease, an inherited disorder causing copper poisoning in the brain and liver.
Description: Rabbit polyclonal to ATP7B
Immunogen: KLH conjugated synthetic peptide derived from ATP7B
Specificity: ·Reacts with Human, Mouse, Pig and Rat.
·Isotype: IgG
Application: ·Western blotting: 1/200-1000. Predicted Mol wt: 157 kDa;
·Immunohistochemistry (Frozen/paraffin tissue section): 1/100-500;
·Immunocytochemistry: 1/100-500;
·ELISA: 1/1000;
·Optimal working dilutions must be determined by the end user.
