Background: TRIP has an N-terminal RING finger motif and a putative coiled-coil domain. A similar murine protein interacts with TNFR-associated factor 1 (TRAF1), TNFR-associated factor 2 (TRAF2), and cylindromatosis. The interaction with TRAF2 inhibits TRAF2-mediated nuclear factor kappa-B, subunit 1 activation that is required for cell activation and protection against apoptosis.
Description: Rabbit polyclonal to TRIP
Immunogen: KLH conjugated synthetic peptide derived from TRIP
Specificity: ·Reacts with Human, Mouse, Dog, Cow, Rabbit and Rat.
·Isotype: IgG
Application: ·Western blotting: 1/200-500. Predicted Mol wt: 53 kDa;
·Immunohistochemistry (Paraffin/frozen tissue section): 1/100-500;
·Immunocytochemistry: 1/200;
·ELISA: 1/1000;
·Optimal working dilutions must be determined by the end user.
