Background: The NUMB and Numb-like genes are essential during nervous system development. Numb proteins function to maintain the self-renewal properties of all neural progenitor cells and could play similar roles in stem-cell maintenance in other tissues. Mice ablated for either NUMB or Numb-like in the nervous system are born normally, however deletion of both genes results in embryonic lethality.
Description: Rabbit polyclonal to NUMB
Immunogen: KLH conjugated synthetic peptide derived from NUMB
Specificity: ·Reacts with Human, Mouse and Rat.
·Isotype: IgG
Application: ·Western blotting: 1/100-500. Predicted Mol wt: 70 kDa;
·Immunohistochemistry (Frozen/paraffin tissue section): 1/100-500;
·Immunocytochemistry: 1/100-200;
·ELISA: 1/500;
·Optimal working dilutions must be determined by the end user.
