Background: Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. ITGA7 encodes integrin alpha chain 7. Integrin alpha 7 undergoes post translational cleavage within the extracellular domain resulting in disulfide linked light and heavy chains that join with beta 1. Integrin alpha 7/beta 1 is the primary laminin receptor on skeletal myoblasts and adult myofibers. Expression of the alpha 7 integrin gene (ITGA7) is developmentally regulated during the formation of skeletal muscle.
Description: Rabbit polyclonal to Integrin alpha 7
Immunogen: KLH conjugated synthetic peptide derived from Integrin alpha 7
Specificity: ·Reacts with Human, Mouse and Rat.
·Isotype: IgG
Application: ·Western blotting: 1/100-500. Predicted Mol wt: 129 kDa;
·Immunohistochemistry (Paraffin/frozen tissue section): 1/100-500;
·Immunocytochemistry: 1/100-200;
·ELISA: 1/500;
·Optimal working dilutions must be determined by the end user.
