Background: ADAMTS genes are primarily expressed in fetal tissues, including the lung, kidney and liver. ADAMTS-15 is a weak aggrecanase expressed in the fetal kidney and liver. It cleaves the interglobular domain of aggrecan, separating the G1 and G2 domains. In human breast carcinoma, low expression levels of ADAMTS-15 together with high expression levels of ADAMTS-8 is associated with a greater risk for recurrence and death.
Description: Rabbit polyclonal to ADAMTS15
Immunogen: KLH conjugated synthetic peptide derived from ADAMTS15
Specificity: ·Reacts with Human, Mouse and Rat.
·Isotype: IgG
Application: ·Western blotting: 1/100-500. Predicted Mol wt: 103 kDa;
·Immunohistochemistry (Paraffin/frozen tissue section): 1/100-500;
·Immunocytochemistry: 1/100-200;
·ELISA: 1/500;
·Optimal working dilutions must be determined by the end user.
