Background: ADAMs are expressed in a wide range of mammalian tissues and several are abundantly expressed in the male reproductive tract. ADAM28, also designated MDC-L, is more closely related to snake venom metalloproteases (SVMPs) than to other ADAM family members. ADAM28 displays a high level of expression in lymphocytes and epididymis, and functions mainly on the cell surface, where it mediates cell adhesion through its binding to integrin a4b1. The gene encoding human ADAM28 maps to chromosome 8p12.
Description: Rabbit polyclonal to ADAM28
Immunogen: KLH conjugated synthetic peptide derived from ADAM28
Specificity: ·Reacts with Human, Mouse and Rat.
·Isotype: IgG
Application: ·Western blotting: 1/100-500. Predicted Mol wt: 87 kDa;
·Immunohistochemistry (Paraffin/frozen tissue section): 1/50-200;
·Immunocytochemistry/Immunofluorescence: 1/100;
·Immunoprecipitation: 1/50;
·ELISA: 1/500;
·Optimal working dilutions must be determined by the end user.
