Background: FSTL5 (follistatin-like protein 5), also known as KIAA1263, is an 847 amino acid secreted protein that contains 2 EF-hand domains, 2 Ig-like (immunoglobulin-like) domains and a Kazal-like domain. The gene encoding FSTL5 maps to human chromosome 4q32.2 and murine chromosome 3 E3. Human chromosome 4 represents approximately 6% of the human genome and contains nearly 900 genes. Notably, the Huntingtin gene, which is found to encode an expanded glutamine tract in cases of Huntington’s disease, is located on chromosome 4. FGFR-3 is also encoded by a gene that maps to human chromosome 4 and is associated with thanatophoric dwarfism, achondroplasia, Muenke syndrome and bladder cancer. Chromosome 4 is also tied to Ellis-van Creveld syndrome, methylmalonic acidemia and polycystic kidney disease.
Description: Rabbit polyclonal to FSTL5
Immunogen: KLH conjugated synthetic peptide derived from FSTL5
Specificity: ·Reacts with Human, Mouse and Rat.
·Isotype: IgG
Application: ·Western blotting: 1/100-500. Predicted Mol wt: 96 kDa;
·Immunohistochemistry (Paraffin/frozen tissue section): 1/50-200;
·Immunocytochemistry/Immunofluorescence: 1/100;
·Immunoprecipitation: 1/50;
·ELISA: 1/500;
·Optimal working dilutions must be determined by the end user.
