Background: NDRG2 (NDRG family member 2) may be involved in dendritic cell and neuron differentiation. It is a cytoplasmic protein. Highly expressed in brain, heart, skeletal muscle and salivary gland, and moderately in kidney and liver. Expressed in dendritic cells, but not in other blood cells. Generally not expressed in tumor cell lines. Isoform 1 and isoform2 are present in brain neurons and up-regulated in Alzheimer disease (at protein level). Not expressed or strongly down-regulated in various cancer types, such as astrocytoma, meningioma, liver cancer and pancreatic cancer. May have anti-tumor activity. Belongs to the NDRG family.
Description: Rabbit polyclonal to NDRG2
Immunogen: KLH conjugated synthetic peptide derived from NDRG2
Specificity: ·Reacts with Human, Mouse and Rat.
·Isotype: IgG
Application: ·Western blotting: 1/100-500. Predicted Mol wt: 41 kDa;
·Immunohistochemistry (Frozen/paraffin tissue section): 1/100-500;
·Immunocytochemistry: 1/200;
·ELISA: 1/500;
·Optimal working dilutions must be determined by the end user.
