Background: Ribosomes, the organelles that catalyze protein synthesis, are composed of a small subunit (40S) and a large subunit (60S) that consist of over 80 distinct ribosomal proteins. Mammalian ribosomal proteins are encoded by multigene families that contain processed pseudogenes and one functional intron-containing gene within their coding regions. Ribosomal Protein L15, also known as RPL15, EC45 or RPLY10, is a 204 amino acid protein that localizes to the cytoplasm and functions as a component of the 60S subunit, playing a role in protein translation. Existing as multiple alternatively spliced isoforms, Ribosomal Protein L15 is overexpressed in esophageal and gastric tumors, suggesting a role in carcinogenesis. Like most ribosomal proteins, Ribosomal Protein L9 exists as multiple processed pseudogenes that are scattered throughout the genome.
Description: Rabbit polyclonal to RPL15
Immunogen: KLH conjugated synthetic peptide derived from RPL15
Specificity: ·Reacts with Human, Mouse and Rat.
·Isotype: IgG
Application: ·Western blotting: 1/100-500. Predicted Mol wt: 24 kDa;
·Immunohistochemistry (Paraffin/frozen tissue section): 1/100-500;
·Immunocytochemistry/Immunofluorescence: 1/100;
·Immunoprecipitation: 1/50;
·ELISA: 1/500;
·Optimal working dilutions must be determined by the end user.
