Background: Encephalopsin is the first putative extraocular opsin identified in mammals and may play a role in encephalic photoreception. Also designated Panopsin, encephalopsin may play a role in non-visual photic processes such as the entrainment of circadian rhythm or the regulation of pineal melatonin production. Encephalopsin shows strong and specific expression in the brain. In the cortex and cerebellum, encephalopsin expression is considerably higher and more highly patterned in the adult than in the neonate. In addition to encephalopsin, other classical visual opsins Rgr-opsin, peropsin and melanopsin are all expressed in fetal development by E11.5, unlike the murine rod and cone opsins that exhibit post-natal expression, such as P1 for ultraviolet cone opsin and P5 for rod opsin.
Description: Rabbit polyclonal to Encephalopsin
Immunogen: KLH conjugated synthetic peptide derived from Encephalopsin
Specificity: ·Reacts with Human, Mouse and Rat.
·Isotype: IgG
Application: ·Western blotting: 1/100-500. Predicted Mol wt: 45 kDa;
·Immunohistochemistry (Paraffin/frozen tissue section): 1/100-500;
·Immunocytochemistry/Immunofluorescence: 1/100;
·Immunoprecipitation: 1/50;
·ELISA: 1/500;
·Optimal working dilutions must be determined by the end user.
